Sore throats - should we treat them?

Patients often come to the doctor with a sore throat wondering
whether there is any treatment that will shorten the course of
disease. It is worth examining the major causes of sore throats
to determine what should be done.
The best known germ that can cause sore throats and
tonsillitis is the Streptococcus. In fact only 10% of adults and
less than 30% of children with sore throats have a Streptococcal
infection. The majority of the rest are caused by viruses. Your
doctor cannot tell whether a sore throat is caused by a
Streptococcus or by a virus just by looking at the back of the
mouth. It is possible to grow Streptococci from throat swabs. The
results often come back after the sore throat has settled-not
particularly useful. Additionally, some people are carriers of
the Streptococcal germ and yet it does not cause symptoms. It is
possible to grow these germs even if the sore throat is actually
caused by a virus.
How about treatment?
We have no effective treatment for the viruses that cause most
sore throats. Viruses differ from bacteria by using our own body's
cells to multiply and cause infection. We cannot poison them with
antibiotics-anything that stops the virus reproducing is likely
to damage normal human tissue as well. We have to rely on our own
immune system to mop up the infection. Usually it does a good,
efficient job. However, there are thousands of different viruses.
Each infection requires the immune system to start from fresh; to
get up to speed usually takes 2-4 days. During this time you have
the flu-like symptoms and sore throat. These are largely due to
your immune system's normal response to infection and are a sign
that you are fighting the germs.
Should we treat sore throats with antibiotics?
If the sore throat is a caused by a virus (most are) then
clearly not. What if it caused by a Streptococcus bacteria? This
is contentious. Firstly, it is difficult to establish that the
Streptococcus is responsible for the sore throat-it will be so
only in the minority of infections and may be present as an
innocent bystander. Secondly, we need to know whether treatment
really makes a difference. On average, treating a Streptococcal
sore throat will reduce the duration of symptoms by 12-24 hours
only. In other words, it makes little difference to short term
symptom control. The published evidence suggests that treatment
does not reduce the subsequent development of rheumatic fever
after a Strep sore throat, and complications such as quinsy are
rare so that treating all sore throats with penicillin is more
likely to cause side effects than benefit. Moreover, the
streptococci causing sore throats are not killed by penicillin in
approximately 1 in 6 infections, so penicillin treatment is no
guarantee of cure.
In summary, most sore throats are caused by viruses, the vast
majority will get better on their own and treatment with
antibiotics is ineffective in most cases. At best it might reduce
the duration of the sore throat by 24 hours. If you take
paracetamol regularly for the fever and pain and sit the
infection out; it should get better within a few days and there
is little we can do to speed up your recovery. If you feel your
problem is different from an ordinary sore throat, we are always
willing to see you and advise appropriately. Do not, however,
expect an automatic prescription!

