Viruses: what are they and can we treat them?

Viruses, unlike other microorganisms such as bacteria, cannot reproduce
independently. A virus has to enter a living organism and take control of some
host cells in order to make more copies of itself. Viruses are very specific in
their choice of host. There is little cross infection between animals and
humans. The majority of viruses are well adapted to their host (i.e. you) and
usually cause a self limiting illness.
A virus enters your body by being swallowed with food or drink, licked off
fingers, inhaled in an aerosol of tiny virus particles from somebody's sneeze,
transferred skin to skin, injected into the bloodstream or transmitted sexually.
Whichever route is a particular virus's favourite, it will only attach itself to
certain cells in your body that carry a protein on their surface that the virus
recognises as a "receptor" for itself. Once attached to the receptor on a cell
the virus inserts its nucleic acid (its genetic code), and sometimes a few
proteins that help it reproduce.
Viruses are dependent on your own body processes to reproduce. The virus's
genetic code is not dissimilar to human nucleic acid (your genes) and the virus
uses your body's own processes to make more copies of the virus genetic code and
proteins. These are assembled into virus particles and go on to infect other
cells or people. When a virus makes more copies of itself it may or may not kill
the cell it is using. This depends on the type of virus.
Your body can recognise when it is infected by a virus. The virus leaves tell
tale signs that your immune system can detect. Your immune system responds by
producing more immune system cells and a variety of chemicals. In combination
these stop your body making more virus and kill virus infected cells. The body
also produces antibodies that prevent virus spread within your body and give
lasting immunity from further infection by that strain of virus.
Unfortunately, all this immune system activity is responsible for the 'flu
symptoms that are common with viral infections. Fever, localised pain, headache,
muscle and joint aches all contribute to make you feel miserable. Paracetamol
will help to minimise these. Console yourself that your flu-like symptoms are
there because you are mounting an efficient response to the virus.
Because viruses depend on your own body processes to reproduce, it is
difficult to design drugs that inhibit this process without simultaneously
damaging your cells. Regrettably antibiotics used to treat bacterial infections
will not be the slightest use in stopping a virus infection. There are just a
handful of antiviral treatments for particular infections only. For the vast
majority of viruses that you will catch there is no treatment that the doctor
can offer you to speed recovery. Fortunately most viral infections are self
limiting-the body is efficient at clearing the infection within a few days.
Typical infections that are due to viruses include the common cold. Any
illness characterised by fever and a runny nose whether or not this is
accompanied by sore throat, headache, muscle and joint pains, is probably due to
a virus. There are thousands of strains of viruses that cause these symptoms and
it would be impossible to become immune to all of them. The treatment here is
paracetamol and time.
Most sore throats are caused by viruses and will not respond to antibiotics.
Most chest infections described as "flu" are due to viruses such as influenza
and parainfluenza. Again antibiotics will not help. Usually these are self
limiting illnesses and will settle, although the residual cough often continues
for several weeks after the virus infection is controlled. Paracetamol will help
to control the 'flu symptoms.
Childhood diarrhoea and vomiting is usually due to a viral infection. The
treatment is adequate fluid replacement using a balanced electrolyte replacement
such as Dioralyte if the diarrhoea is profuse. Diarrhoea may continue for a week
or more but your child can eat normally.

